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Total 19438 results found since Jan 2013.

Cardiovascular Parameters in a Swine Model of Normobaric Hypoxia Treated With 5-Hydroxymethyl-2-Furfural (5-HMF)
Conclusion: 5-HMF treatment decreased P50, improved SaO2, and mitigated increases in PAP in this swine model of NH. Introduction The reduction of barometric pressure at altitude is associated with reduced partial pressure of ambient Oxygen (PO2). With lower ambient PO2, it can be anticipated that alveolar (PAO2), arterial O2 (PaO2) and blood O2 content (CaO2) will decrease accordingly, resulting in a widely recognized decrease in maximal O2 consumption (VO2) (Dill and Adams, 1972; Lucas et al., 2011). In humans, with acute exposure to altitude, maximal VO2 decrements are measurable at elevations even as low as 580 ...
Source: Frontiers in Physiology - April 17, 2019 Category: Physiology Source Type: research

Protective effects of nicorandil against cerebral injury in a swine cardiac arrest model.
Authors: Zhu F, Zhong X, Zhou Y, Hou Z, Hu H, Liang L, Chen J, Chen Q, Ji X, Shang D Abstract The present study investigated the effects of nicorandil on cerebral injury following cardiopulmonary resuscitation (CPR) in a swine model of cardiac arrest. CPR was performed on swine following 4 min induced ventricular fibrillation. Surviving animals were randomly divided into 3 groups: A nicorandil group (n=8), a control group (n=8) and a sham group (n=4). The sham group underwent the same surgical procedure to imitate cardiac arrest, but ventricular fibrillation was not induced. When the earliest observable return of s...
Source: Experimental and Therapeutic Medicine - July 8, 2018 Category: General Medicine Tags: Exp Ther Med Source Type: research

Intracranial Space–occupying Lesion Inducing Intracranial Hypertension Increases the Encephalographic Effects of Isoflurane in a Swine Model
Conclusions: ICSOLs inducing intracranial hypertension increase the EEG effect of isoflurane, and external compression from the brain surface enhances the anesthetic hypnosis despite minimum brain injury.
Source: Journal of Neurosurgical Anesthesiology - December 11, 2018 Category: Anesthesiology Tags: Laboratory Investigation Source Type: research

The Search for the Elusive Elixir of Life
By TOM EMERICK Here’s the executive summary: Most disease and health spending is age-related. As we age we get infirmities ranging from dementia to cancer to vascular disease. Nothing can prevent aging. Period. For millennia mankind has been been on a futile search to prevent aging. Search for the Elusive Elixir of Life For 3500 or more years mankind has been searching for the mythological Elixir of Life, the fountain of youth, the philosophers stone, pool of nectar, etc, that will defeat aging and extend life, if not achieve immortality. According to Wiki, “The elixir of life, also known as the elixir of immortality a...
Source: The Health Care Blog - February 4, 2016 Category: Consumer Health News Authors: Simon Nath Tags: THCB Tom Emerick Source Type: blogs

Characterizing internet search patterns for neurologic and neurosurgical conditions following celebrity diagnosis
CONCLUSIONS: Following major events related to the neurological disease of public figures there is an expected rise in Google search interest relevant to these topics. Our findings suggest that there is an optimal window of approximately 2 weeks following each of these events for activist and clinical groups to publicize their desired message, and for the field of neurosurgery and neurological science to increase public awareness regarding specific diseases, with a regression to baseline interest by 4-months following the event.PMID:34763394 | DOI:10.23736/S0390-5616.21.05569-7
Source: Journal of Neurosurgical Sciences - November 12, 2021 Category: Neurosurgery Authors: Max S Ward Michael J Feldman Brittany N Ward Vera Ong Nolan J Brown Shane Shahrestani Chen Y Yang Mickey E Abraham Boris Paskhover Anil Nanda Source Type: research

Jess Search, Doc Society Co-Founder, Dies at 54
Jess Search, producer and co-founder of U.K.’s Doc Society, has died. She was 54. Search died in London on July 31 following a brain tumor diagnosis in early June. Search was a near two-decade member and co-founder of the U.K. based Doc Society, a non-profit organization started in 2005 dedicated…#jesssearch #docsociety #docsocietys #todayiam #maxyne #megha #shanida #garysnyder #virunga #livingwithtudors
Source: Reuters: Health - August 2, 2023 Category: Consumer Health News Source Type: news

Cancers, Vol. 13, Pages 3028: Co-Deregulated miRNA Signatures in Childhood Central Nervous System Tumors: In Search for Common Tumor miRNA-Related Mechanics
Conclusions: Our approach could prove significant in the search for global miRNA targets for tumor diagnosis and therapy. To the best of our knowledge, there are no previous reports concerning the present approach.
Source: Cancers - June 17, 2021 Category: Cancer & Oncology Authors: George I. Lambrou Apostolos Zaravinos Maria Braoudaki Tags: Article Source Type: research